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Anal cancer is an uncommon malignancy that starts in the anus-- the opening at the end of the rectum. The american society of clinical oncology estimates that 8,300 cases of anal cancer will be. With anal cancer, malignant cells grow in the tissues of the anus. Infection with the human papillomavirus (hpv) increases your risk. A lump near the anus, anal discharge, bleeding, itching, and pressure are signs and symptoms. At first, most people assume the bleeding is caused by hemorrhoids (painful, swollen veins in the anus and rectum that may bleed). Colon cancer is a growth of abnormal cells in the colon, which multiply causing cancerous tumors. Internal, external, and ruptured hemorrhoids are swollen blood vessels and painful inflammation near the anus. Both colon cancer and hemorrhoids can cause rectal bleeding, blood in stool, and the feeling that you have not completed a bowel movement. The symptoms of anal cancer are often similar to more common and less serious conditions affecting the anus, such as piles (haemorrhoids) and small tears or sores called anal fissures. Sometimes abnormal cells on the inner surface layer of the anus look like cancer cells but have not grown into any of the deeper layers. This is known as carcinoma in situ, (pronounced in sy-too), or cis. What causes anal cancer? Nearly all (90) anal cancers are attributable to persistent infection with hpv, the cause of genital warts. Certain strains of hpv are known to be oncogenic (cancer-causing), especially types hpv 16 and 18, and these two infections cause more than 90 of anal cancers. Rarely, subtyping of hpv has detected low-risk strains such as hpv 6 or multiple strains of hpv.

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